![]() The meta-analysis showed that combined vitamin D plus calcium supplementation has a significant effect on the reduction in the risk of falls (OR for the risk of suffering at least one fall, 0.87 95% CI, 0.80-0.94). We included only double-blind randomized, controlled trials (RCTs) of vitamin D in elderly populations that examined fall results.Ī total of 26 articles were included in which 16,540 elderly individuals received vitamin D supplementation, while 16,146 were assigned to control groups. Two authors working independently reviewed the trials, and odds ratios (ORs) were calculated using a fixed-effect or random-effect model by Review Manager 5.3. The PubMed and Cochrane Library databases were searched from the earliest possible year up to December 2016. We conducted this meta-analysis to assess the effect of vitamin D on falls among elderly individuals. A number of studies have hypothesized that vitamin D is a potential factor in the prevention of falls in the elderly however, the effect of vitamin D is still inconsistent and not quantitative.
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